한국인에서 중합효소반응을 이용한 short tandem repeat 유전좌위 F13A01 유전자형 및 대립유전자 빈도
Genotype and allele frequency of the short tandem repeat F13AO1 locus by polymerase chain reaction in Korean
이영수, 장명규,
소속 상세정보
이영수 ( ) - 조선대학교 치과대학 구강내과학
장명규 ( ) - 조선대학교 치과대학 구강내과학
KMID : 0355219960210020317
Abstract
Allelic frequency and genotype distribution of short tandem repeat(STR) F13AO1 locus was analysed by polymerase chain reaction, polyacrylamide gel electrophoresis and silver staining from human genomic deoxyribonucleic acid(DNA) was extracted from 205 unrelated Korean to be applied to forensic identification and parentage testing as a database.
The results were as-foflows
1. 5 alleles and 11 genotypes of F13AO1 locus were detected and heterozygosity value was 62.0% and the observed
each alleles and allelic frequency was 3.2(0.363). 4(0.105), 5(0.063), 6(0.466), 16(0.002).
2. The allelic diversity value was 0.639 and the power of discrimination was 0.804.
3. Compared with observed number of alleles and allele frequency in ethnic difference, result was appeared to be
similar to that of Japanese and Asians, while -Was appeared to be much different to that of Blacks .and Caucasians
in the observed number of alleles and frequency of allele 3.2, 5, 7.
From the above result of this investigation, the allelic frequency of STR F13A01 locus in the Korean was considerd to be useful for individual identification and parentage testing as a database.
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